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Differentiating Neurogenic and Vascular Claudication

Robert McCabe, DPT, SCS, OCS, CSCS, MTC

February 1, 2025

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Question

How can clinicians differentiate between neurogenic and vascular claudication in patients with lumbar stenosis?

Answer

Neurogenic and vascular claudication share similar symptoms, such as leg pain and heaviness, but have distinct underlying mechanisms and clinical presentations. Neurogenic claudication results from nerve root compression or ischemia due to spinal canal narrowing, while vascular claudication stems from insufficient blood flow to the lower extremities.

Patients with neurogenic claudication often report pain exacerbated by lumbar extension, standing, or walking. Symptoms improve with flexion-based activities like sitting or leaning forward, as this posture widens the spinal canal. In contrast, vascular claudication is typically provoked by both walking and bicycling, as these activities increase demand on the circulatory system. Patients with vascular claudication do not experience symptom relief in a flexed position.

Special tests, such as the two-stage treadmill test or the bicycle stress test, can help differentiate between these conditions. For example, patients with neurogenic claudication may tolerate longer walking distances on an inclined treadmill or bicycling in a slouched position, as these reduce lumbar extension. In contrast, vascular claudication patients experience consistent pain regardless of posture or incline. Recognizing these differences is critical for accurate diagnosis and effective treatment planning.

This Ask the Expert is an edited excerpt from the course, "Evaluation and Treatment of Lumbar Spinal Stenosis," presented by Robert McCabe, DPT, SCS, OCS, CSCS, MTC.


robert mccabe

Robert McCabe, DPT, SCS, OCS, CSCS, MTC

Bob has over 30 years of experience working in orthopedics and sports medicine. He is currently a sports physical therapist and research coordinator at the Orlando Health Jewett Orthopedic Institute. His prior experience includes working in private practice, at the Andrews Institute Rehabilitation, and as the Director of Human Performance for the Airforce Special Operations Command (AFSOC). He is dual-certified by the APTA as an orthopedic specialist and sports clinical specialist.  He also holds certifications in manual therapy through Evidence in Motion and is an NSCA-certified strength and conditioning coach.  Bob has published several articles in peer-reviewed journals and has presented research at national meetings.  


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